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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRCH3 All Species: 8.48
Human Site: S643 Identified Species: 20.74
UniProt: Q96II8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96II8 NP_116162.1 777 86083 S643 P T T D S T D S I T G Q N S R
Chimpanzee Pan troglodytes XP_001167088 777 86063 S643 P T T D S T D S I T G Q N S R
Rhesus Macaque Macaca mulatta XP_001118364 784 87008 S650 P T T D S A D S I T R Q N S R
Dog Lupus familis XP_549199 765 84379 N655 Q I R Q L R N N L E S R L K V
Cat Felis silvestris
Mouse Mus musculus Q8BVU0 778 86321 A640 P A T D P T D A I T R Q R E E
Rat Rattus norvegicus NP_001100558 526 58586 D424 V K P I A V R D F Q K T E D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516723 729 81318 Q612 E D L E S I N Q L R K N I E F
Chicken Gallus gallus Q5ZLN0 603 67457 I501 A L T R L Q V I N L S F N R F
Frog Xenopus laevis NP_001090023 601 66754 R499 L R K D I E S R L P V T L R E
Zebra Danio Brachydanio rerio Q7SXW3 601 67297 V499 G L I K L R S V I L S F N R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 81.6 44.2 N.A. 87.7 60.3 N.A. 74.7 21.7 39.7 21.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 84.3 60.4 N.A. 92 63.5 N.A. 80.3 38.4 51.9 38 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 0 N.A. 53.3 0 N.A. 6.6 13.3 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 26.6 N.A. 60 6.6 N.A. 26.6 13.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 10 10 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 50 0 0 40 10 0 0 0 0 0 10 0 % D
% Glu: 10 0 0 10 0 10 0 0 0 10 0 0 10 20 20 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 20 0 0 30 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 10 10 10 10 0 10 50 0 0 0 10 0 0 % I
% Lys: 0 10 10 10 0 0 0 0 0 0 20 0 0 10 0 % K
% Leu: 10 20 10 0 30 0 0 0 30 20 0 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 20 10 10 0 0 10 50 0 0 % N
% Pro: 40 0 10 0 10 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 10 0 0 10 0 10 0 10 0 10 0 40 0 0 0 % Q
% Arg: 0 10 10 10 0 20 10 10 0 10 20 10 10 30 30 % R
% Ser: 0 0 0 0 40 0 20 30 0 0 30 0 0 30 0 % S
% Thr: 0 30 50 0 0 30 0 0 0 40 0 20 0 0 0 % T
% Val: 10 0 0 0 0 10 10 10 0 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _